Subscribe

Noises In and Around Joint Signal Future Knee Osteoarthritis

VBCR - April 2018, Vol 7, No 1 - Osteoarthritis
Anne Rowe
Noises In and Around Joint Signal Future Knee Osteoarthritis

Patients’ subjective complaints of crepitus (ie, hearing grating, popping, or cracking sounds in and/or around a joint) can predict the development of symptomatic knee osteoarthritis (OA) in the absence of symptoms such as pain, according to the results of a recent study (Lo GH, et al. Arthritis Care Res (Hoboken). 2018;70:53-60).

“Subjective knee crepitus can be used clinically to identify individuals at risk for symptomatic OA, potentially assisting with earlier diagnosis and ultimately with intervention,” wrote lead investigator Grace H. Lo, MD, MSc, Assistant Professor, Section of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, and colleagues.

The investigators evaluated the right knee only using data from the Osteoarthritis Initiative, a longitudinal, observational study of knee OA conducted at 4 clinical sites: Memorial Hospital of Rhode Island (Pawtucket), Ohio State University (Columbus), University of Pittsburgh, and University of Maryland/Johns Hopkins University (Baltimore). Patients were aged 45 to 79 years at the time of enrollment in the initiative (February 2004-May 2006). They underwent body mass index assessment at baseline, as well as evaluation for the presence of crepitus and symptoms at baseline and annual follow-up visits.

The study focused on 3495 patients without baseline symptomatic OA. The investigators assessed frequent knee pain and radiographs at baseline and at annual visits up to 48 months. They also assessed crepitus frequency at baseline and at 12, 24, and 36 months using the following question from the Knee Injury and Osteoarthritis Outcome Score: Do you feel grinding, or hear clicking or any other type of noise when your right knee moves?

At the beginning of the study, 65.1% of patients said they had no crepitus, 10.8% said they experienced it “rarely,” 15.1% said they had it “sometimes,” 5.6% said they had it “often,” and 3.4% said they experienced it “always.” Overall, 636 (18.1%) patients developed symptomatic OA of the knee during the study period.

The odds of developing incident symptomatic knee OA was higher among patients with greater frequency of crepitus (P <.0001). They also found that patients who had radiographic OA but who lacked symptoms at baseline comprised 26% of this group, but >75% of the incident symptomatic OA cases.

Although crepitus frequency resulted in larger odds ratios for incident symptomatic OA in men versus women and in older versus younger patients, crepitus was predictive of incident symptomatic OA in all subgroups.

“Subjective crepitus is a simple and effective assessment that is predictive of the longitudinal development of symptomatic OA. It may offer utility for the identification of at-risk individuals, predictive modeling, and future clinical and epidemiologic research,” the investigators concluded.

Related Items
Medical Groups Applaud Congressional Leaders for Agreement to Repeal Medicare Therapy Caps
Anne Rowe
VBCR - December 2017, Vol 6, No 5 published on December 19, 2017 in Health Policy
ACR Responds to 2019 Benefit and Payment Parameters Proposed Rule
Anne Rowe
VBCR - December 2017, Vol 6, No 5 published on December 19, 2017 in Health Policy
Retired UK Professional Football Players at Higher Risk for Knee OA Than Men in the General Population
Anne Rowe
VBCR - December 2017, Vol 6, No 5 published on December 19, 2017 in Osteoarthritis
Sustained Disease Remission Increased by Adding Tocilizumab to Glucocorticoid Therapy in Patients with Giant-Cell Arteritis
Anne Rowe
VBCR - October 2017, Vol 6, No 4 published on October 20, 2017 in Giant Cell Arteritis
Smartphone Application May Help Patients with Lupus Report Their Symptoms in Real Time
Anne Rowe
VBCR - October 2017, Vol 6, No 4 published on October 20, 2017 in Technology Update
New Algorithm Shows Promise in Predicting Progression of Knee Osteoarthritis
Rebecca Bailey
VBCR - October 2017, Vol 6, No 4 published on October 20, 2017 in Osteoarthritis
Opioid Use Before Knee Replacement Surgery Leads to Worse Pain Outcomes
Anne Rowe
VBCR - August 2017, Vol 6, No 3 published on August 23, 2017 in Osteoarthritis
Higher Fish Consumption Associated with Lower RA Disease Activity
Anne Rowe
VBCR - August 2017, Vol 6, No 3 published on August 23, 2017 in Rheumatoid Arthritis
Motivational Counseling and Text Reminders Improve Outcomes in Patients with RA
Anne Rowe
VBCR - August 2017, Vol 6, No 3 published on August 23, 2017 in Rheumatoid Arthritis
High-Fiber Diet Associated with Reduced Risk for Painful Knee Osteoarthritis
Anne Rowe
VBCR - August 2017, Vol 6, No 3 published on August 23, 2017 in Osteoarthritis
Last modified: May 4, 2018
  • Rheumatology Practice Management
  • Lynx CME
  • American Health & Drug Benefits
  • Value-Based Cancer Care
  • Value-Based Care in Myeloma
  • Value-Based Care in Neurology