Fibromyalgia

Review of Appeals of Fibromyalgia-Related Workplace Injury Compensation Cases Sheds Light on the Medicolegal Aspects of the Disease

By Rosemary Frei, MSc

Winnipeg, Manitoba—There are lessons for rheumatologists and for family physicians in how courts adjudicate cases of fibromyalgia that were alleged to have been caused by or exacerbated by workplace injury, according to a new study presented at the Canadian Pain Society’s 2013 annual meeting and was published simultaneously (Fitzcharles MA, et al. J Rheumatol. 2013;40:323-328).

Impact of Pain on Quality of Life in Patients with Fibromyalgia

By Rosemary Frei, MSc

Winnipeg, Manitoba—A study on the influence of pain and catastrophizing on quality of life in patients with fibromyalgia has answered some questions and raised others.

Impaired Brain Processing and Other Effects of Fibromyalgia

By Phoebe Starr

The way patients with fibromyalgia experience pain may be a result of abnormal pain signal processing associated with reduced opioid receptor binding, according to a study presented during the 2012 meeting of the American College of Rheumatology.

Patients with Fibromyalgia Improve Rapidly with Pregabalin

First Japanese clinical trial for this condition
By Charles Bankhead

Patients with fibromyalgia had significant improvement in pain, sleep, and quality-of-life mea­sures when treated with pregabalin (Lyrica) versus placebo, according to the results of the first clinical trial of this condition in Japan (Ohta H, et al. Arthritis Res Ther. 2012;14:R217 [Epub ahead of print]). Significant pain relief occurred within the first week of treatment with pregabalin and persisted over the 15-week duration of the trial. Significantly more patients reported being “very much improved” or “much improved” with pregabalin than with placebo (P = .078).

Motivation Interviewing of Patients with Fibromyalgia to Encourage Exercise Provides Mixed Results

By Rosemary Frei, MSc

An intense program of telephone support does not have a significant effect on the motivation of patients with fibromyalgia to exercise or on their disease symptoms, according to the first randomized study to expressly address exercise in this patient population (Ang DC, et al. Clin J Pain. 2012 Oct 5 [Epub ahead of print]).

Childhood Abuse Linked to Pain and Depression in Patients with Fibromyalgia

By Rosemary Frei, MSc

Milan, Italy—The combination of childhood emotional abuse and current depression gives rise to higher pain sensitivity, a new study has shown. In a poster presented at the 2012 World Congress on Pain, a group of Belgian researchers showed that among patients with fibromyalgia who suffered childhood emotional abuse, a strong positive correlation exists between depression levels and pain sensitivity. The same correlation does not exist in patients who did not have emotional abuse when they were young.

Relationship between Fibromyalgia and Smoking Still Not Clear

Milan, Italy—A cross-sectional study has uncovered a smoking gun, but it is unclear who the victims are. A University of Michigan group presented evidence at the 2012 World Congress on Pain that patients with pain who meet the 2011 American College of Rheumatology (ACR) survey criteria for fibromyalgia and who smoke have worse neuropathic pain […]

Fibromyalgia: New Insights into a Complex Syndrome

By Sy Schlager, MD, PhD

Although completely misunderstood and often maligned, fibromyalgia (FM) is a functional somatic syndrome estimated to affect 2% to 4% of the population, with a female to male incidence ratio of approximately 4:1.