Using data from 2 US trials, Dr Dai and colleagues performed a meta-analysis with the goal of determining whether dietary fiber may have any bearing on risks for x-ray evidence of knee OA, symptomatic knee OA (eg, pain and stiffness), and worsening knee pain.
Advances in contemporary imaging techniques have led to more widespread use of this modality for the management of osteoarthritis (OA). However, in the absence of evidence-based guidelines, imaging is often used in circumstances where it does not change management.
Patients with, or at high risk for, knee osteoarthritis who consume higher amounts of dietary total or cereal grain fiber were less likely to experience moderate and severe knee pain compared with patients whose dietary intake of fiber was lower, according to the results of a recent study by Zhaoli Dai, PhD, MS, Postdoctoral Fellow, Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, MA, and colleagues.
Although some observational studies suggest that vitamin D supplementation is beneficial for knee osteoarthritis (OA), a randomized, placebo-controlled, double-blind study called VIDEO found no benefit for vitamin D supplementation on pain reduction or change on tibial cartilage volume in patients with symptomatic knee OA and low endogenous vitamin D levels.
London, United Kingdom—Rheumatologists are fully aware of the impact of rheumatoid arthritis (RA) on patients’ lives, but underestimate the severity and impact of osteoarthritis (OA), according to the researchers of a study that looked at physician and patient perceptions of global disease status in both conditions.
The age-related cartilage wear that occurs in macroscopically normal joints and is evident at the superficial zone indicates that the wear-protective function of synovial fluid (SF) and wear resistance of cartilage changes with aging, and may lead to osteoarthritis (OA).
Individuals at high risk for osteoporotic fracture constitute a very meaningful disease burden to society, particularly in Asia, and that burden is expected to increase significantly in coming years, according to Nicholas Harvey, MA, MB, BChir, MRCP, PhD.
Paris, France—Three biomarkers have been identified that may be used to determine disease severity in osteoarthritis (OA), according to data presented at the 2014 European League Against Rheumatism (EULAR) Congress. The miRNAs—miR 454, miR 885-5p, and miR let-7e—may predict the development of severe OA in patients with early disease.
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Results 1 - 10 of 22
Results 1 - 10 of 22