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Osteoarthritis

Patients with, or at high risk for, knee osteoarthritis who consume higher amounts of dietary total or cereal grain fiber were less likely to experience moderate and severe knee pain compared with patients whose dietary intake of fiber was lower, according to the results of a recent study by Zhaoli Dai, PhD, MS, Postdoctoral Fellow, Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, MA, and colleagues.
Although some observational studies suggest that vitamin D supplementation is beneficial for knee osteoarthritis (OA), a randomized, placebo-controlled, double-blind study called VIDEO found no benefit for vitamin D supplementation on pain reduction or change on tibial cartilage volume in patients with symptomatic knee OA and low endogenous vitamin D levels.
London, United Kingdom—Rheumatologists are fully aware of the impact of rheumatoid arthritis (RA) on patients’ lives, but underestimate the severity and impact of osteoarthritis (OA), according to the researchers of a study that looked at physician and patient perceptions of global disease status in both conditions.
The age-related cartilage wear that occurs in macroscopically normal joints and is evident at the superficial zone indicates that the wear-protective function of synovial fluid (SF) and wear resistance of cartilage changes with aging, and may lead to osteoarthritis (OA).
A review of the literature has shown strength training, stretching, and flexibility exercises are of significant benefit to people with mild-to-moderate hip osteoarthritis.
Individuals at high risk for osteoporotic fracture constitute a very meaningful disease burden to society, particularly in Asia, and that burden is expected to increase significantly in coming years, according to Nicholas Harvey, MA, MB, BChir, MRCP, PhD.
Paris, France—Three biomarkers have been identified that may be used to determine disease severity in osteo­arthritis (OA), according to data presented at the 2014 European League Against Rheumatism (EULAR) Congress. The miRNAs—miR 454, miR 885-5p, and miR let-7e—may predict the development of severe OA in patients with early disease.
Tampa, FL—Current guidelines for the management of knee osteoarthritis (OA) from the American Academy of Orthopaedic Surgeons do not recommend intra-articular hyaluronic acid (IAHA) injection (ie, viscosupplementation) for patients with symptomatic OA because of the lack of data indicating that its use reduces pain.
Tampa, FL—The grey wave that is washing over the United States will mean many more people will need help coping with their osteoarthritis pain, according to presenters at a symposium during the American Pain Society’s 2014 Annual Meeting.
Contemporary guidelines for the management of osteoarthritis (OA) from different stakeholder organizations are generally consistent, according to a systematic review of the literature undertaken as an initiative of the Chronic Osteoarthritis Management Initiative Work Group.
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