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Gout

Although the efficacy of febuxostat has been shown in el­derly patients, its efficacy is unclear in elderly women with hyperuricemia.
Gout affects 1% to 2% of adults in Western countries and 2.5% of adults in the United Kingdom. Compared with the general population, patients with gout have increased cardiovascular morbidity and mortality, and researchers largely attribute this increased risk to urate levels.
Previous research suggests that gouty arthritis (GA) is associated with an increased risk for certain disorders, such as cardiovascular (CV) disease. Inger L. Meek, MD, and colleagues recently reported that hyperuricemia was associated with a 3.1-fold hazard of first CV event in patients with GA.
Vancouver, British Columbia—A study of 143 men with hematospermia revealed that approximately 15% also had hyperuricemia.
Charlotte, NC—How many rheumatologists can say they can cure gout? Not many can confidently say so, according to an informal poll taken during the 2014 North Carolina Rheumatology Association annual meeting.
By Phoebe Starr San Diego, CA—Patients with gout and elevated serum uric acid levels are not receiving optimal urate-lowering therapy (ULT), according to the results of an international prospective study reported at the 2013 American College of Rheumatology meeting.
By Wayne Kuznar San Diego, CA—A high percentage of patients with gout treated by rheumatologists are not at treatment goals as recognized by the American College of Rheumatology (ACR), even after 6 months or more of higher-dose urate-lowering therapy (ULT), according to the results from a national survey. Patients with more severe disease were less likely to be at treatment goal.
By Rosemary Frei, MSc A new multicenter study confirms that there is an independent association between gout and gout-related characteristics on the one hand and functional impairment and quality of life on the other. For example, polyarticular joint involvement is significantly associated with increased disability and with poorer overall quality of life for this patient population (Scirè CA, et al. Arthritis Res Ther. 2013;15:R101).
By Rosemary Frei, MSc Montreal, Quebec—Dual-energy computed tomography (DECT) has value in gout diagnosis and management, according to a presentation at the Canadian Association of Radiologists’ 2013 annual meeting.
By analyzing information from the National Health and Nu­trition Examination Survey (NHANES) from 1988-1994 and 2007-2010, researchers have uncovered a 30% rate of gout prevalence among Americans with severe chronic kidney disease (CKD). They also found significantly higher rates of gout among individuals with lower average estimated glomerular filtration rates (eGFRs) or higher levels of albuminuria, even after adjusting for uric acid levels (Juraschek SP, et al. Semin Arthritis Rheum. 2013 Jan 8 [Epub ahead of print]). By Rosemary Frei, MSc
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